Register for the
2014 HMS Epigenetics Symposium

December 1, 2014

Upcoming Events


BBS Program in Genetics and Genomics Annual Symposium

Goldenson, Room 122

DNA Double-Strand Break Repair and Maintenance of Genome Stability in Mammalian Cells

Genetics Seminar Series

Dissecting the embryo with single-cell RNA-Seq

BCH Division of Genetics and Genomics Seminar

To Be Announced


2014 HMS Epigenetics Symposium

Merck Research Labs, 33 Avenue Louis Pasteur, Boston MA
Arabidopsis 2

Welcome to Genetics at Harvard

Reflecting the breadth of the field itself, the Department of Genetics at Harvard Medical School houses a faculty working on diverse problems, using a variety of approaches and model organisms, unified in their focus on the genome as an organizing principle for understanding biological phenomena. Genetics is not perceived simply as a subject, but rather as a way of viewing and approaching biological phenomena.

While the range of current efforts can best be appreciated by reading the research interests of individual faculty, the scope of the work conducted in the Department includes (but is by no means limited to) human genetics of both single gene disorders and complex traits, development of genomic technology, cancer biology, developmental biology, signal transduction, cell biological problems, stem cell biology, computational genetics, immunology, synthetic biology, epigenetics, evolutionary biology and plant biology.

The mission of our Department encompasses research and education while serving as a focal point for drawing together and integrating basic and clinical genetic efforts conducted across the University and its affiliated hospitals. The Department of Genetics is strongly committed to supporting its current community of faculty, postdoctoral fellows and graduate students and to securing the best new scientists, setting its sight on new research opportunities in the future.

In the News

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Congratulations to Frederick Alt, Recipient of the 44th Rosenstiel Award for Distinguished Work in Biomedical Science for elucidating the mechanisms of genome rearrangements in immune and cancer cells.

The Rosenstiel Award was established at Brandeis University in 1971 “as an expression of the conviction that educational institutions have an important role to play in the encouragement and development of basic science as it applies to medicine.”

Meet the Faculty

Jeannie T. Lee, M.D., Ph.D.
Our lab studies how male (XY) and female (XX) cells use a mechanism called X-chromosome inactivation to achieve equality of sex chromosome gene expression. Our studies are focused on three noncoding RNA loci whose actions coordinate the many steps of X-chromosome inactivation. We are also interested in the mechanistic and evolutionary relationship between X inactivation and imprinting. Recent work by the Lee Lab suggests that imprinted X-chromosome inactivation is directly connected to meiotic sex...