Home

Register for the
2014 HMS Epigenetics Symposium

December 1, 2014

Upcoming Events

Department Halloween Party

NRB 2nd Floor Sky Lobby
Seminar

DNA Double-Strand Break Repair and Maintenance of Genome Stability in Mammalian Cells

Genetics Seminar Series

Dissecting the embryo with single-cell RNA-Seq

BCH Division of Genetics and Genomics Seminar

To Be Announced

Conference

2014 HMS Epigenetics Symposium

Merck Research Labs, 33 Avenue Louis Pasteur, Boston MA
Arabidopsis 1

Welcome to Genetics at Harvard

Reflecting the breadth of the field itself, the Department of Genetics at Harvard Medical School houses a faculty working on diverse problems, using a variety of approaches and model organisms, unified in their focus on the genome as an organizing principle for understanding biological phenomena. Genetics is not perceived simply as a subject, but rather as a way of viewing and approaching biological phenomena.

While the range of current efforts can best be appreciated by reading the research interests of individual faculty, the scope of the work conducted in the Department includes (but is by no means limited to) human genetics of both single gene disorders and complex traits, development of genomic technology, cancer biology, developmental biology, signal transduction, cell biological problems, stem cell biology, computational genetics, immunology, synthetic biology, epigenetics, evolutionary biology and plant biology.

The mission of our Department encompasses research and education while serving as a focal point for drawing together and integrating basic and clinical genetic efforts conducted across the University and its affiliated hospitals. The Department of Genetics is strongly committed to supporting its current community of faculty, postdoctoral fellows and graduate students and to securing the best new scientists, setting its sight on new research opportunities in the future.

In the News

no image

Congratulations to Frederick Alt, Recipient of the 44th Rosenstiel Award for Distinguished Work in Biomedical Science for elucidating the mechanisms of genome rearrangements in immune and cancer cells.

The Rosenstiel Award was established at Brandeis University in 1971 “as an expression of the conviction that educational institutions have an important role to play in the encouragement and development of basic science as it applies to medicine.”

Meet the Faculty

no image
The Alt laboratory studies mechanisms that maintain genomic stability in mammalian cells. The programmed recombination and hypermutation events in lymphocytes and the general DNA repair mechanisms involved in these processes are a focus. The laboratory also studies mechanisms that promote and prevent oncogenic translocations.  Approaches range from molecular genetics and biochemistry to animal models.