Stephen J. Elledge, Ph.D.
Stephen
Elledge
We study the cellular response to genotoxic stress. We have uncovered a signal transduction protein kinase cascade that phosphorylates over 700 proteins in response to DNA damage and controls genomic stability. Using synthetic biology we also develop genetic technologies such as genome-wide viral libraries of shRNAs for genetic screening in mammals to identify genes important for cancer and growth control.
Contact:
Department of Genetics
Harvard Medical School
NRB 158D
77 Avenue Louis Pasteur
Boston, MA 02115
phone: (617) 525-4510
email: selledge [at] genetics [dot] med [dot] harvard [dot] edu
Department of Genetics
Harvard Medical School
NRB 158D
77 Avenue Louis Pasteur
Boston, MA 02115
phone: (617) 525-4510
email: selledge [at] genetics [dot] med [dot] harvard [dot] edu