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Genomics has made revolutionary progress in the almost 20 years since the inception of the Human Genome Project. However, we are still far from achieving the ultimate goal of systems biology, the development of comprehensive models of biological processes that can accurately predict a cell's response to novel genetic and environmental perturbations. Understanding biological systems at this level of detail will require numerous technological advances, including the ability to measure the abundance of all components of a biological system on an absolute scale, to incorporate spatial and temporal dynamics, and to relate all of this information back to the function or fitness of the organism.
On this site I, summarize my current work and future plans, which are focused on developing genomic technologies to address many of these issues.
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