Noa Liberman, Ph.D.

Post-doctoral Research Fellow

Noa LibermanResearch Interest: Over the course of evolution, most of the mitochondrial genome has either been lost or transferred to the nuclear genome. However, mitochondria still retain a small part of their genome, requiring the nuclear and mitochondrial genomes to closely coordinate their activities, as each encodes different subunits of the same complexes of the oxidative phosphorylation (OXPHOS) system. Our lab has shown that mitochondrial dysfunction in aging muscle tissue is at least in part the consequence of a loss of balance in the expression of mitochondrial versus nuclear encoded OXPHOS subunits. I am interested in understanding the significance of this coordination and unbalanced expression in organismal and organ aging.


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