Log on to the webmail interface by going to https://receptor.med.harvard.edu and
entering your username and your password.
You should see something like this:

Click on the link that
says 'Options' . You will then see
the 'Options' screen. Scroll down
towards the bottom and you will see the link 'Vacation Message/ Message
Forwarding'. Click on this link.

You want to check mark the
box that says 'Send Auto-Reply to Sender'. In the 'Vacation Subject' box type whatever you want the
subject of your vacation message to be.
In the 'Vacation Message' type what you would like the body of your
message to say. Then click on the
'Change Settings' button.