| 2007 |
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Hsiau, T.H., Diaconu, C., Myers, C.A., Lee, J., Cepko, C.L., Corbo, J.C.(2007). The cis-regulatory logic of the mammalian photoreceptor transcriptional network. PLoS ONE 2(7):e643. Download PDF.
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Corbo, J.C., Myers, C.A., Lawrence, K.A., Jadhav, A.P., Cepko, C.L. (2007) A typology of photoreceptor gene expression patterns in the mouse. Proc. Natl. Acad. Sci. USA 104(29):12069-74. Download PDF. |
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Chen, B., Cepko, C.L. (2007). Requirement of histone deacetylase activity for the expression of critical photoreceptor genes. BMC Dev. Biol. 7(1):78. Download PDF.
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Trimarchi, J.M., Stadler, M.B., Roska, B., Billings, N. Sun, B., Bartch, B., Cepko, C.L. (2007). Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J. Comp. Neurol. 502(6)1047-1065. Download PDF.
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Punzo, C., Cepko, C.L. (2007). Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration. Invest. Ophthalmol. Vis. Sci. 48(2):849-57. Download PDF. |
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Matsuda, T., Cepko, C.L. (2007). Controlled expression of transgenes introduced by in vivo electroporation. Proc. Natl. Acad. Sci. USA 104(3):1027-32. Download PDF. |
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Jadhav, A.P., Cho, S.H., Cepko, C.L. (2006). Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. Proc. Natl. Acad. Sci. USA 103(50):18998-9003. Download PDF. |
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Cho, S.H., Cepko, C.L. (2006). Wnt2b/{beta} catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133(16):3167-77. Download PDF.
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Young-Pearse, T.L., Ivic, L., Kriegstein, A.R., Cepko, C.L. (2006). Characterization of mice with targeted deletion of glycine receptor alpha 2. Molecular & Cellular Biology 26(15):5728-34. Download PDF.
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Jadhav, A.P., Mason, H.A., and Cepko, C.L. (2006). Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development 133(5):913-22. Download PDF. |
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Harpavat, S., Cepko, C.L. (2006). RCAS-RNAi: a loss-of-function method for the developing chick retina. BMC Developmental Biology 133(5):913-22. Download PDF. |
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Sen, J., Harpavat, S., Peters, M.A., and Cepko, C.L. (2005). Retinoic acid regulates the expression of dorsoventral topographic guidance molecules in the chick retina. Development 132(23):5147-5159. Download PDF.
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Corbo, J., Cepko, C. (2005). A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-Cone Syndrome. PloS Genetics1(2):0140-??. Download PDF. |
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Rowan S., Cepko, C. (2005). A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells.Developmental Biology 281(2):240-55. Download PDF.
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Young, T.L., Matsuda, T., and Cepko, C.L. (2005). The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Curr Biol 15(6):501-512. Download PDF. |
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Morrow, E.M, Furukawa, T, Raviola, E, and Cepko, C.L. (2005). Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice. BMC Neuroscience 6:5. Download PDF. |
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Schulte, D, Peters, M.A, Sen, J, and Cepko, C.L. (2005). The rod photoreceptor pattern is set at the optic vesicle stage and requires spatially restricted cVax expression. J Neuroscience 25(11):2823-31. Download PDF. |
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Blackshaw, S, Harpavat, S, Trimarchi, J, Cai, L, Huang, H, Kuo, W, Lee, K, Fraioli, R, Cho, S, Yung, R, Asch, E, Wong, W, Ohno-Machado, L, Weber, G,, Cepko, C.L. (2004). Genomic Analysis of Mouse Retinal Development. PLoS Biology 2(9):E247. Download PDF.
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Rowan S, Cepko, C. (2004). Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multi-functional BAC transgenic mouse reporter. Developmental Biology 271(2):388-402. Download PDF. |
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Rowan S, Chen A, Young TL, Fisher DE, Cepko CL. (2004). Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development 131:5139-5152. Download PDF.
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Young TL, Cepko CL. (2004). A role for ligand-gated ion channels in rod photoreceptor development. Neuron 41:867-879. Download PDF. |
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Livesey FJ, Young TL, Cepko CL. (2004). An analysis of the gene expression program of mammalian neural progenitor cells. Proc Natl Acad Sci U S A 101:1374-1379. Download PDF. |
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Matsuda, T, Cepko CL. (2004). Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc Natl Acad Sci U S A 101:16-22. Download PDF. |
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Harpavat, S., Cepko CL. (2003). Thyroid hormone and retinal development: an emerging field. Thyroid 13(11):1013-9. Download PDF. |
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Blackshaw S, Kuo WP, Park PJ, Tsujikawa M, Gunnerson, JM, Scott HS, Boon W-M, Tan S-S, Cepko CL. (2003). MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues. Genome Biology 4:R17.1-R17.15. Download PDF. |
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Blackshaw S, Cepko CL. (2002). Stem cells that know their place. Nat Neurosci 5(12):1251-1252. Download PDF.
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Chen CM, Cepko CL. (2002). The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation. Development 129:5363-5375. Download PDF. |
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Peters MA, Cepko CL. (2002). The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments. Dev Biol. 251:59-73. Download PDF. |
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Szele FG, Chin HK, Rowlson MA, Cepko CL. (2002). Sox-9 and cDachsund-2 expression in the developing chick telencephalon. Mech. Dev. 112:179-82. Download PDF. |
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Blackshaw S, Fraioli RE, Furukawa T, Cepko CL. (2001). Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell 107:579-589. Download PDF.
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Cepko CL. (2001). Tackling the brain's genetic complexity. Nat Neurosci. Suppl:1159-60. Download PDF. |
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Livesey FJ, Cepko CL. (2001). Neurobiology. Developing order. Nature 413(6855):471, 473. Download PDF.
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Dyer, M.A., Cepko, C.L. (2001). p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. J. Neurosci. 21:4259-71. Download PDF. |
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Dyer MA, Cepko CL. (2001). Regulating proliferation during retinal development. Nature Reviews– Neuroscience 2(5):333-42. Download PDF.
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Livesey FJ, Cepko CL. (2001). Vertebrate neural cell-fate determination: lessons from the retina. Nature Reviews–Neuroscience 2(2):109-18. Download PDF. |
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Lin, J.C., Cai, L., Cepko, C.L. The external granule layer of the developing chick cerebellum generates granule cells and cells of the isthmus and rostral hindbrain. J. Neurosci. 21:159-168 (2001). Download PDF.
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Dyer, M.A. and Cepko, C.L. The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina. J. Comp. Neurol. 429: 601-14 (2001). Download PDF. |
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Cepko, CL. Genomics approaches to photoreceptor development and disease. Harvey Lect . 97:85-110 (2001-2002). Download PDF. |
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Schulte, D. and Cepko, C.L. Two homeobox genes define the domain of EphA3 expression in the developing chick retina. Development, 127(23): 5033-45. (2000). Download PDF. |
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Dyer, M.A. and Cepko, C.L. Control of Muller glial cell proliferation and activation following retinal injury. Nature Neuroscience 3(9):873-80 (2000). Download PDF. |
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Dyer, M.A. and Cepko, C.L. p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development 127(16):3593-605 (2000). Download PDF. |
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Cai, L., E.M. Morrow and Cepko, C.L. Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development 127(14):3021-30 (2000). Download PDF. |
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Furukawa, T., S. Mukherjee, Z.Z. Bao, E.M. Morrow and Cepko, C.L. rax, Hes1, and notch1 promote the formation of Muller glia by postnatal retinal progenitor cells. Neuron. 26(2):383-94 (2000). Download PDF. |
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Livesey, F., Furukawa T, Steffen MA, Church GM, Cepko, C.L. Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene crx. Current Biology 10:301-310 (2000). Download PDF. |
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Belliveau, M.J., Young, T. and Cepko, C.L. Late retinal progenitors show intrinsic limitations in the production of cell types and the kinetics of opsin synthesis. J. Neurosci. 20:2247-2254 (2000). Download PDF. |
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Cepko C. Giving in to the blues. Nature Genetics 24:99-100 (2000). Download PDF. |
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Chen, C.-M.A., and Cepko, C.L. Expression of Chx10 and Chx10-1 in the developing chicken retina. Mech. Dev. 90:293-297 (2000). Download PDF. |
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Cepko, CL, Ryder, E, Austin, C, Golden, J, Fields-Berry, S, and Lin, J. Lineage analysis with retroviral vectors. Methods Enzymol . 327:118-45 (2000). Download PDF. |
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| 1999 |
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Schulte, D., Furukawa, T., Peters, M.A., Kozak, C.A., and Cepko, C.L. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map. Neuron 24:541-553 (1999). Download PDF. |
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Furukawa, T., Morrow, E.M., Li, T., Davis, F.C., and Cepko, C.L. Retinopathy and attenuated circadian entrainment in Crx-deficient mice. Nature Genetics 23: 466-470 (1999). Download PDF. |
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Chen, C.M., Smith, D.M., Peters, M.A., Samson, M.E., Zitz, J., Tabin, C.J., and Cepko, C.L. Production and design of more effective avian replication-incompetent retroviral vectors. Developmental Biology 214: 370-384 (1999). Download PDF. |
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Lin J.C., and Cepko, C.L. Biphasic dispersion of clones containing Purkinje cells and glia in the developing chick cerebellum. Developmental Biology 211: 177-197 (1999). Download PDF. |
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Cepko, C.L. The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Curr. Opin. Neurobiol. 9: 37-46 (1999). |
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Bao, Z.-Z., Benoit, G.B., Seidman, J.G., Seidman, C.E. and Cepko, C.L. Regulation of Chamber-Specific Gene Expression in the Developing Heart by Irx4. Science 283: 1161-1164 (1999). Download PDF. |
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Belliveau, M.J. and Cepko, C.L. Extrinsic and intrinsic factors control the genesis of amacrine and cone cells in the rat retina. Development 126: 555-566 (1999). Download PDF. |
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Morrow, E.M., Furukawa, T., Lee, J.E. and Cepko, C.L. NeuroD regulates multiple functions in the developing neural retina in rodent. Development 126: 23-36 (1999). Download PDF. |
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| 1998 |
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Lin J.C. and Cepko, C.L. Granule cell raphes and parasagittal domains of Purkinje cells: complementary patterns in the developing chick cerebellum. J. Neurosci. 18: 9342-9353 (1998). Download PDF. |
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Morrow, E.M., Furukawa, T. and Cepko, C.L. Vertebrate photoreceptor cell development and disease. Trends Cell Biol. 8: 353-358 (1998). Download PDF. |
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Ma, C., Papermaster, D. and Cepko, C.L. A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice. Proc. Natl. Acad. Sci. USA 95: 9938-9943 (1998). Download PDF. |
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Morrow, E.M., Belliveau, M.J. and Cepko, C.L. Two phases of rod photoreceptor differentiation during rat retinal development. J Neurosci. 18: 3738-3748 (1998). Download PDF. |
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Cepko, C.L., Ryder, E., Austin, C., Golden, J., Fields-Berry, S. and Lin, J. Lineage analysis using retroviral vectors. Methods 14: 393-406 (1998). Download PDF. |
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Szele, F.G. and Cepko, C.L. The dispersion of clonally related cells in the developing chick telencephalon. Dev. Biol. 195: 100-113 (1998). Download PDF. |
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| 1997 |
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Furukawa, T., Morrow, E.M. and Cepko, C.L. Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell 91: 531-541 (1997). Download PDF. |
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Golden, J.A., Zitz, J.C., McFadden, K. and Cepko, C.L. Cell migration in the developing chick diencephalon. Development 124: 3525-3533 (1997). Download PDF. |
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Furukawa, T., Kozak, C.A. and Cepko, C.L. Rax, a novel paired-type homeobox gene, shows expression restricted to anterior neural fold and developing retina. Proc. Natl. Acad. Sci. USA 94: 3088-3093 (1997). Download PDF. |
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Alexiades, M.R. and Cepko, C.L. Subsets of retinal progenitors display temporally regulated and distinct biases in the fates of their progeny. Development 124: 1119-1131 (1997). Download PDF. |
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Ezzeddine, Z.D., Yang, X., DeChiara, T., Yancopoulos, G. and Cepko, C.L. Postmitotic cells fated to become rod photoreceptors can be respecified by CNTF treatment of the retina. Development 124: 1055-1067 (1997). Download PDF. |
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Bao, Z-Z. and Cepko, C.L. The expression and function of Notch pathway genes in the developing rat eye. J. Neuroscience 17: 1425-1434 (1997). Download PDF. |
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| 1996 |
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Szele, F.G. and Cepko, C.L. A subset of clones in the chick telencephalon are arranged in rostrocaudal arrays. Current Biology 6: 1685-1690 (1996). Download PDF. |
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Yang, X. and Cepko, C.L. Flk-1, a receptor for Vascular Endothelial Growth Factor (VEGF), is expressed by retinal progenitor cells. J. Neuroscience 16: 6089-6099 (1996). Download PDF. |
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Cepko, C.L. The patterning and onset of opsin expression in vertebrate retinae. Curr. Opin. Neurobiology 6: 542-546 (1996). Download PDF. |
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Alexiades, M.R. and Cepko, C.L. Quantitative analysis of proliferation and cell cycle length during development of the rat retina. Devel. Dynamics 205: 293-307 (1996). Download PDF. |
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Bruhn, S.L. and Cepko, C.L. Development of the pattern of photoreceptors in the chick retina. J. Neuroscience 16: 1430-1439 (1996). Download PDF. |
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Cepko, C.L., Austin, C.P., Yang, X., Alexiades, M., Ezzeddine, D. Cell fate determination in the vertebrate retina. Proc. Natl. Acad. Sci. USA 93: 589-595 (1996). Download PDF. |
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Arnold-Aldea, S.A. and Cepko, C.L. Dispersion patterns of clonally related cells during development of the hypothalamus. Devel. Biol. 173: 148-161 (1996). Download PDF. |
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Golden, J.A. and Cepko, C.L. Clones in the chick diencephalon contain multiple cell types and siblings are widely dispersed. Development 122: 65-78 (1996). Download PDF. |
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